PHYSICAL AND CHEMICAL PROPERTIES

Physical Data
Boiling Point :27.6 C(81.7 F) @ 760 mm Hg
Vapour Pressure : 13 psia @ 25 C (77F)
Vapour Density : 5.3 (Air=1.0)
%Volatiles : 100 WT%
Evaporation Rate : <1 (CCl4=1.0)
Solubility in Water : 0.39 WT% @ 25 C (77 F)
pH : Neutral
Odor : Ether (Slight).
Form : Liquid.
Color : Clear,Colorless.
Liquid Density : 1.46 g/cm3 @ 25 C(77 F)

HEALTH HAZARD/FIRST AID MEASURES

HAZARDS IDENTIFICATION

Inhalation of high concentrations of vapor is harmful and may cause heart irregularities, unconsciousness. or death. Intentional misuse or deliberate inhalation may cause death without warning. Vapor reduces oxygen available for breathing and is heavier than air. Product causes mild eye irritation. Decomposition products are hazardous.

HEALTH HAZARDS:

Eye contact may cause irritation with discomfort, tearing, or blurring of vision Overexposure by inhalation may cause liver damage with altered enzyme levels, and temporary nervous system depression with anesthetic effects such as dizziness, weakness, headache, confusion, incoordination, and loss of consciousness. With ‘overexposure (>2%), possibly temporary alteration of the heart’s electrical activity with irregular pulse, palpitations, or inadequate circulation. Increased susceptibility to the effects of this material may observed in persons with pre-existing disease of the central nervous system, cardiovascular system, and liver.

Carcinogenicity Information

None of the components present in this material at concentrations equal to or greater than 0.1% are listed by IARC, NTP, OSHA or ACGIH as a carcinogen.

FIRST AID MEASURES

First Aid

INHALATION

If high concentrations are inhaled, immediately remove to fresh air. Keep person calm. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician.

SKIN CONTACT

In case of contact, flush with water. Get medical attention if irritation is present.

EYE CONTACT

In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Call a physician

INGESTION

Material poses an aspiration hazard. If swallowed, do not induce vomiting Immediately give 2 glasses of water. Never give anything by mouth to an unconscious person_ Call a physician.
If vomiting occurs naturally, have victim lean forward to reduce the risk of aspiration.

Notes to Physicians

THIS MATERIAL MAY MAKE THE HEART MORE SUSCEPTIBLE TO ARRHYTHMIAS.
Catecholamines such as adrenaline, and other compounds having similar effects, should be reserved for emergencies and then used only with special caution.

FIRE AND EXPLOSION HAZARDS/ FIRE FIGHTING MEASURES

FIRE FIGHTING MEASURES

# Flammable Properties Flash Point No flash point Flammable Limits in air. % by Volume.
LEL : None per ASTM E681
UEL . None per ASTM E681
Autoignition Not determined

Extinguishing Media

Use media appropriate for surrounding material.

Fire Fighting Instructions

Cool tank/container with water spray. Self-contained breathing apparatus (SCBA) is required if drums rupture and contents are
spilled under fire conditions. Water runoff should be contained and neutralized prior to release.

ACCIDENTAL RELEASE MEASURES

Safeguards (Personnel)

NOTE: Review FIRE FIGHTING MEASURES and HANDLING (PERSONNEL) sections before proceeding with clean-up. Use appropriate
PERSONAL PROTECTIVE EQUIPMENT during clean-up. Ventilate spill area

Refex Emergency Exposure Limits (EEL) are established to facilitate site or plant emergency evacuation and specify airborne concentrations of brief durations which should not result in permanent adverse health effects or interfere with escape. EEL’s are expressed as airborne concentration multiplied by time (CxT) for up to a maximum of 60 minutes and as a ceiling airborne concentration. These limits are used in conjunction with engineering controls/monitoring and as an aid in planning for episodic releases and spills. For more information on the applicability of EEL’s, contact Refex.

The Refex Emergency Exposure Limit (EEL) for HCFC-123 is 1000 ppm for up to 60 minutes with a 1 minute not-to-exceed ceiling of 2500 ppm.

HANDLING, STORAGE, SPILL, EXPOSURE CONTROLS AND
DISPOSAL INFORMATION

Initial Containment

Dike spill. Prevent material from entering sewers, waterways, or low areas.

Spill Clean Up

Collect on absorbent material and transfer to steel drums for recovery/disposal. Comply with Federal, State, and local regulations for reporting releases.

HANDLING AND STORAGE

Handling (Personnel)

Avoid breathing high concentrations of vapor. Provide adequate ventilation for storage, handling, and use, especially for enclosed or low spaces. Avoid contact of liquid with eyes and prolonged skin exposure.

Handling (Physical Aspects)

Do not allow product to contact open flame or electrical heating elements because dangerous decomposition products may form.

Storage

Store in a clean, dry place.
Do not heat above 52 deg C to avoid over pressurizing the container.

EXPOSURE CONTROLS/PERSONAL PROTECTION

Engineering Controls

Use only with adequate ventilation. Keep container tightly closed. Vapors are heavier than air posing a hazard of asphyxia if they are trapped in enclosed or low places.

Personal Protective Equipment

EYE/FACE PROTECTION

Wear safety glasses or coverall chemical splash goggles.

RESPIRATORS

Where there is potential for airborne exposures in excess of applicable limits, wear NIOSH approved respiratory
protection.

PROTECTIVE CLOTHING

Where there is potential for skin contact have available and wear as appropriate impervious gloves, apron. pants, and jacket

Exposure Guidelines

Exposure Limits

“REFEX” 123
PEL (OSHA) : None Established
TLV (ACGIH) None Established
AEL * (Refex) : 50 ppm, 8 & 12 Hr. TWA
VVEEL (AIHA) 50 ppm, 8 Hr. TWA
AEL is Refex’s Acceptable Exposure Limit. Where governmentally imposed occupational exposure limits which are lower than the AEL are in effect, such limits shall take precedence.

DISPOSAL CONSIDERATIONS

Waste Disposal
Recover by distillation or remove to a permitted waste disposal facility.

STABILITY AND REACTIVITY DATA

Chemical Stability : Stable.
Conditions to Avoid : Avoid open flames and high temperatures.
Incompatibility with Other Materials Incompatible with alkali or alkaline earth metals – powdered Al, Zn, Be, etc
Decomposition:Decomposition products are hazardous This material can be decomposed by high temperatures (open flames, glowing metal
surfaces, etc.) forming hydrochloric and hydrofluoric acids, and possibly carbonyl halides. These materials are toxic and irritating. Contact should be avoided.
Polymerization will not occur

TOXICOLOGICAL AND ECOLOGICAL INFORMATION

TOXICOLOGICAL INFORMATION

Animal Data
HCFC-123
Dermal ALD, rabbit: >2000 mg/kg
Oral ALD, rat: 9000 mg/kg
Inhalation 4 hour, LC50, rat: 32,000 ppm
Animal testing indicates that HCFC-123 is not a skin irritant or skin sensitizer, but is a mild to moderate eye irritant.

Toxic effects noted in animals from single exposure by inhalation at concentrations of 5000 ppm or greater include effects on unconditioned reflexes, locomotor activity and coordination.

suggesting anesthetic effects. Single inhalation exposures caused central nervous system effects, such as anesthesia, and nonspecific clinical signs and organ pathology changes. Cardiac sensitization occurred in dogs at concentrations of 20,000 ppm and greater Repeated exposures to 300 ppm and higher resulted in decreased cholesterol, triglycerides or glucose, and increased urinary fluoride levels At 5000 ppm or greater, anesthetic effects, reduced lymphocyte counts, organ weight changes, including increased liver weight. and enzyme alterations, and decreased body weight gain were observed. Exposure to dogs, guinea pigs or monkeys at 1000 ppm or greater induced slight or mild liver damage. HCFC-123 was not neurotoxic in animals repeatedly exposed by inhalation at concentrations up to 5,000 ppm. but did cause a slight decrease in arousal at this concentration. Long-term exposure caused decreased body weight, decreased cholesterol, triglycerides and glucose, and increased urinary fluoride concentrations in rats. Inhalation of 300, 1000 or 5000 ppm for two years caused an increase in benign testicular tumors in male rats. An increase in benign pancreatic and liver tumors was observed in rats exposed to 1000 or 5000 ppm. The tumors were late-occurring and none were judged to be life-threatening The biological significance of these tumors to man is considered to be limited. Additionally, evidence of retinal atrophy was observed in this two-year study in both treated and control animals, although the toxicological significance is undetermined. Animal data indicate that HCFC­123 does not affect.
reproductive performance in rats or harm the unborn animal. HCFC-123 does not produce genetic damage in bacterial cell cultures or in animals. In two studies, genetic damage was produced in mammalian cell cultures, but did not produce genetic damage in another study. Overall weight of evidence indicates that HCFC-123 is not mutagenic.

ECOLOGICAL INFORMATION

Ecotoxicological Information

AQUATIC TOXICITY:
Slightly toxic
96 hour LC50 – Fathead minnows: > 77 mg/L

TRANSPORTATION INFORMATION

Shipping Information

Shipping Containers Tank Cars.
Tank Trucks.
Drums

The data in this Material Safety Data Sheet relates only to the specific material designated herein
and does not relate to use in
combination with any other material or in any process.

Responsible for MSDS:

Refex Refrigerants Limited
#114, Thandalam Village,Thiruporur,
Kanchipuram Dt,603 110.
Tamilnadu, India.

Ph : +91-44-27445295/ 27445295
This information is based upon technical information believed to be reliable. It is subject to revision as additional knowledge and experience is gained.
End of Refex Refrigerants Limited MSDS